Drugs used to treat GORD

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Metoclopramide

Anti emetic use only.

Indication:
Anti emetic use only.

Formulations:
Solution 1mg/ml
Tablets 10mg

Dose:
0.1-0.2mg/kg 6-8 hrly.

Side effects:
Increased gastric motility, extrapyramidal side effects, drowsiness and restlessness.

Interactions:
Increased effects of paracetamol
Opiates and antimuscarinics decrease the effects of metoclopramide
Increased risk of extrapyramidal effects with tetrabenazine.

Drug therapy of gastro-oesphageal reflux