Indication:
To prevent and treat chronic constipation.

Formulation:
Capsule 100mg
Paediatric solution 12.5mg/5ml, Adult solution 50mg/5ml

Dose:
2.5mg/kg tds
Or
< 1 year 12.5mg (bd – tds)
1 – 4 years: 12.5mg – 25mg (bd – tds)
5 – 12 years: 25 – 50mg (bd-tds) Max 200mg daily

Counselling:
Using milk or orange squash can mask the bitter flavour.

Contra-Indications:
Capsules should not be taken in the presence of abdominal pain, nausea, vomiting or intestinal obstruction.

Side effects:
Anal or rectal burning and pain, diarrhoea and rash.

Interactions:
Should not be used concurrently with mineral oil. Anthraquinone derivatives (e.g. senna) should be taken in reduced doses if administered with docusate sodium as their absorption is increased.

Notes:
Acts within 1 to 2 days.