Drugs used in constipation

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Sodium Picosulphate

Stimulant Laxative

Indication:
Treatment of acute or chronic constipation
Bowel clearance prior to colonoscopy

Formulation:
Liquid 5mg/5ml

Dose:
2 – 5 years: 2.5 – 5ml daily
5 – 10 years: 5 – 10ml daily
>10 years: 10 – 15ml daily

Counselling:
Give doses at night if possible.

Contra-Indication:
Undiagnosed abdominal pain or suspected / proven intestinal obstruction.

Side effects:
Mild abdominal discomfort

Interactions:
Sodium picosulphate is broken down by bacteria in the large intestine so it is possible that patients taking broad spectrum antibiotics may experience some loss of laxative action.

Notes:
Onset of action is normally 10 to 14 hours after administration.

Licensing status:
Licensed for children over 2 years of age.