Formulation:
Oral powder

Dose:
Add contents of 1 sachet to 1 litre of water.
Then 10ml/kg/hr for 30min then 20ml/kg/hr for 30min.
If tolerated , increase to 25ml/kg/hr.
Maximum volume is 100ml/kg or 4000ml (whichever is smaller) over 4 hours.

Side effects:
Nausea, abdominal fullness, bloating, abdominal cramps and anal irritation.
Fluid overload or dehydration may occur.
Electrolyte disturbance and hypoglycaemia (see notes)
Urticaria and allergic reactions occur rarely.

Interactions:
Any medication given within one hour of administration of klean prep maybe flushed from the GI tract and not absorbed.

Contra-Indications:
GI obstruction or perforation, ileus, gastric retention, acute gastritis or intestinal ulceration, toxic colitis or megacolon.
Caution in patients with impaired gag reflex or those with gastro-oesphageal relux.
Caution in patients <20kg

Notes:
If adverse effects are suspected, U+E’s and glucose should be monitored or if treatment is to continue beyond 4 hours.
1 sachet / 1000ml water = 125mmol Na+, 10mmol K+, 4mmol SO42-, 35mmol Cl-